About Us

MINEVIK Machinery is a leading and pioneering enterprise with the most advanced international level in R&D, manufacturing and selling of large-scale crushing & screening plants and beneficiation plants.

large-scale crushing & screening plants and beneficiation plants.

All of our equipment have got ISO international quality system certification, European Union CE certification and Russian GOST certification.

  • In central China-Zhengzhou, covering 140 thousand square meters
  • Win-win cooperation and create more value to customers
  • Exported large quantities and high-end mobile crushing plant and milling equipments to Russia, Kazakhstan, Indonesia, Ecuador, South Africa, Nigeria, Turkey more than 100 countries .

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Our Products

AS a leading global manufacturer of crushing and milling equipment, we offer including quarry, aggregate, grinding production and complete stone crushing plant. We also supply individual crushers and mills as well as spare parts of them.

Services

Our goal is to guarantee the excellent operation equipment with high safety for our customers and minimize the downtime of the machine by predictive maintenance. Kefid service and original accessories can be 100% trusted at the time of maintenance.

SERVICE AND SUPPORT

Minevik service and original accessories can be 100% trusted at the time of maintenance.

ACCESSORIES CENTER

striving to enable customers to get the parts in the nearest place.

SALES MARKET

Our sales market is spread all over more than 100 countries and regions

antitubercular screening of natural products from colombian plants 3 methoxynordomesticine an inhibitor of mure ligase of mycoba

Anti-tubercular screening of natural products from

18/08/2010· Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis Juan D. Guzman 1

Anti-tubercular screening of natural product from

Anti-tubercular screening of natural product from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis

Anti-tubercular screening of natural products from

Objectives: New anti-mycobacterial entities with novel mechanisms of action are clinically needed for treating resistant forms of tuberculosis. The purpose of this study was to evaluate anti-tubercular activity and selectivity of seven recently isolated natural products from Colombian plants. Methods: MICs were determined using a liquid medium growth inhibition assay for Mycobacterium...

Anti-tubercular screening of natural products from

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis . Journal of Antimicrobial Chemotherapy, 2010. juan guzman. Sanjib Bhakta. juan guzman. Sanjib Bhakta. Download with Google Download with Facebook or download with email. Anti-tubercular screening of natural products from Colombian plants: 3

Anti-tubercular screening of natural products from

Abstract. New anti-mycobacterial entities with novel mechanisms of action are clinically needed for treating resistant forms of tuberculosis. The purpose of this study was to evaluate anti-tubercular activity and selectivity of seven recently isolated natural products from Colombian plants.\ud \ud MICs were determined using a liquid medium growth inhibition assay for Mycobacterium tuberculosis

About the lab — Birkbeck, University of London

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. (2010) JD Guzman, A Gupta, D Evangelopoulos, C Basavannacharya, LC Pabon,Bhakta, S. Journal of Antimicrobial Chemotherapy 65 (10), 2101-2107.

About the lab — Birkbeck, University of London

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. (2010) JD Guzman, A Gupta, D Evangelopoulos, C Basavannacharya, LC Pabon,Bhakta, S. Journal of Antimicrobial Chemotherapy 65 (10), 2101-2107.

A new plant-derived antibacterial is an inhibitor of

A new plant-derived antibacterial is an inhibitor of efflux pumps in 3.2. Inhibition of MurE ligase. The effect of compound 1 was tested against the recombinant MurE ligase from M. tuberculosis, a key enzyme that participates in the early stages of peptidoglycan biosynthesis. This enzyme is conserved in all bacterial species but selects its natural substrates in a species-specific manner

Screening of Antitubercular Compound Library Identifies

The rapid rise in the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (Mtb) mandates the discovery of novel tuberculosis (TB) drugs...

An antibacterial from Hypericum acmosepalum inhibits

Here we describe the isolation, structural elucidation and antibacterial action of two natural products from H. acmosepalum. Their ability to inhibit the ATP-dependent MurE ligase enzyme from M. tuberculosis, a pivotal enzyme in peptidoglycan biosynthesis, was also assessed. 2. Materials and methods 2.1. Bacterial strains. A standard S.

In Vitro Anti Tubercular Activity of Leaves of Aerva lanata L.

tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. J Antimicrob Chemother. 2010;65:2101-7. 17. Lawal T O, Adeniyi B A, Wan B, et al. In-vitro susceptibility of Mycobacterium tuberculosis to extracts of Uvaria afzelli Scott

An antibacterial from Hypericum acmosepalum inhibits ATP

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis By Sanjib Bhakta and juan guzman Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase

Juan-David Guzman Google Scholar Citations

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis JD Guzman, A Gupta, D Evangelopoulos, C Basavannacharya, LC Pabon,

In silico Studies for Potential Natural Inhibitors for

In this way it was found that, nowadays metabolic pathway enzymes are proposed as a potential drug target against bacteria because bacteria play a crucial role for the survival of organisms and are needed with minimal level. In another study natural inhibitor from Columbian plant was extracted against MurE ligase enzyme of M. tuberculosis 16.

Antimycobacterial Compounds from Piper sanctum |

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. Journal of Antimicrobial Chemotherapy 2010, 65 (10) , 2101-2107. DOI: 10.1093/jac/dkq313.

APORPHINOID ANTAGONISTS OF 5-HT2A RECEPTORS:

Guzman JD, Gupta A, Evangelopoulos D, Basavannacharya C, Pabon LC, Plazas EA, et al. Antitubercular screening of natural products from Colombian plants: 3-Methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. J Antimicrob Chemother. 2010; 65:2101–7.

Antimycobacterial Compounds from Piper sanctum |

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. Journal of Antimicrobial Chemotherapy 2010, 65 (10) , 2101-2107. DOI: 10.1093/jac/dkq313.

Analogues of Disulfides from Allium stipitatum

Anti-tubercular screening of natural prod ucts from Colombian plants: 3-methoxynordomesticine, a n inhibitor of MurE ligase of Myco bacterium tuberculosis . J.

Analogues of Disulfides from Allium stipitatum

18/01/2018· Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. J. Antimicrob. Chemother. 65, 2101–2107

Mycobacterial Diseases Bhattacharya et al, Mycobac Dis

al. (2010) Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. J Antimicrob Chemother 65: 2101-2107. 13. González-Lamothe R, Mitchell G,

In vitro Antibacterial Activity of Thymus vulgaris

Aims: Nowadays, treatment of bacterial infections is one of the most important challenges in the world. Medicinal plants offer a great hope to overcome these needs because of their chemical diversity and their significant role in the drug development. The aim of this study was to

In vitro Anti-mycobacterial activity of selected medicinal

29/10/2013· Tuberculosis (TB) is a global burden with one –third of the world’s population infected with the pathogen Mycobacterium tuberculosis complex and annually 1.4 million deaths occur due to the disease. This high incidence of infection and the increased rate of multi-drug resistant and extensively-drug resistant strains of the organism further complicated the problem of TB control and have

Analogues of Disulfides from Allium stipitatum

29. Guzman, J. D. et al. Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. J. Antimicrob. Chemother. 65, 2101-2107 (2010). 30. Gibbons, S. & Udo, E. E. The effect of reserpine, a modulator of multidrug efflux pumps, on the in vitro activity of

Resazurin reduction assays for screening of anti

To develop simple, rapid, low-cost and robust assays for screening drugs against dormant and actively growing mycobacteria.Methods. Active Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. Related articles in. Web of Science; Google Scholar ; Related articles in PubMed.

Aporphine alkaloids with antitubercular activity isolated

Antitubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis. J. Antimicrob.

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